Former junkie William Lee makes ends meet as an exterminator. But when he and his wife Joan discover the hallucinatory properties of the powder he uses to kill bugs, they become hooked, and their world is changed forever.

In a career dedicated to seeing the unseeable and filming the unfilmable, perhaps only David Cronenberg could really do justice to William S. Burroughs’ controversial novel Naked Lunch. Weaving together elements of Burroughs’ own remarkable biography with the content of the book, Cronenberg’s film steps inside the body and mind of an author to depict the dangerous act of imagination itself from the inside out.